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Citation for Study 967

Citation title: "Conflicting Phylogenetic Signals at the Base of the Metazoan Tree.".

This study was previously identified under the legacy study ID S852 (Status: Published).

Citation

Rokas A., King N., Finnerty J., & Carroll S. 2003. Conflicting Phylogenetic Signals at the Base of the Metazoan Tree. Evolution & Development, 5(4): 346-359.

Authors

• Rokas A.
• King N.
• Finnerty J.
• Carroll S.

Abstract

A phylogenetic framework is essential for understanding the origin and evolution of metazoan development. Despite a number of recent molecular studies and a rich fossil record of sponges and cnidarians, the evolutionary relationships of the early branching metazoan groups to each other and to a putative outgroup, the choanoflagellates, remain uncertain. This situation may be the result of the limited amount of phylogenetic information found in single genes and the small number of relevant taxa surveyed. To alleviate the effect of these analytical factors in the phylogenetic reconstruction of early-branching metazoan lineages, we have cloned multiple protein-coding genes from two choanoflagellates and diverse sponges, cnidarians, and a ctenophore. Comparisons of sequences for a-tubulin, b-tubulin, Elongation Factor 2, HSP90, and HSP70 robustly support the hypothesis that choanoflagellates are closely affiliated with animals. However, analyses of single and concatenated amino acid sequences fail to resolve the relationships either between early branching metazoan groups or between Metazoa and choanoflagellates. We demonstrate that variable rates of evolution among lineages, sensitivity of the analyses to taxon selection and conflicts in the phylogenetic signal contained in different amino acid sequences obscure the phylogenetic associations among the early branching Metazoa. These factors raise concerns about the ability to resolve the phylogenetic history of animals with molecular sequences. A consensus view of animal evolution may require investigations of genome-scale characters.

External links

• DOI: 10.1046/j.1525-142X.2003.03042.x

About this resource

• Canonical resource URI: http://purl.org/phylo/treebase/phylows/study/TB2:S967
• Other versions: Nexus NeXML
• Show BibTeX reference

  		@ARTICLE{TreeBASE2Ref17248,
  	 author = {Antonis  Rokas and Nicole  King and John  Finnerty and Sean B.  Carroll},
  	 title = {Conflicting Phylogenetic Signals at the Base of the Metazoan Tree.},
  	 year = {2003},
  	 keywords = {},
  	 doi = {10.1046/j.1525-142X.2003.03042.x},
  	 url = {},
  	 pmid = {},
  	 journal = {Evolution & Development},
  	 volume = {5},
  	 number = {4},
  	 pages = {346--359},
  	 abstract = {A phylogenetic framework is essential for understanding the origin and evolution of metazoan development. Despite a number of recent molecular studies and a rich fossil record of sponges and cnidarians, the evolutionary relationships of the early branching metazoan groups to each other and to a putative outgroup, the choanoflagellates, remain uncertain. This situation may be the result of the limited amount of phylogenetic information found in single genes and the small number of relevant taxa surveyed. To alleviate the effect of these analytical factors in the phylogenetic reconstruction of early-branching metazoan lineages, we have cloned multiple protein-coding genes from two choanoflagellates and diverse sponges, cnidarians, and a ctenophore. Comparisons of sequences for a-tubulin, b-tubulin, Elongation Factor 2, HSP90, and HSP70 robustly support the hypothesis that choanoflagellates are closely affiliated with animals. However, analyses of single and concatenated amino acid sequences fail to resolve the relationships either between early branching metazoan groups or between Metazoa and choanoflagellates. We demonstrate that variable rates of evolution among lineages, sensitivity of the analyses to taxon selection and conflicts in the phylogenetic signal contained in different amino acid sequences obscure the phylogenetic associations among the early branching Metazoa. These factors raise concerns about the ability to resolve the phylogenetic history of animals with molecular sequences. A consensus view of animal evolution may require investigations of genome-scale characters.}
  }
  		

• Show RIS reference

  		TY  - JOUR
  ID  - 17248
  AU  - Rokas,Antonis 
  AU  - King,Nicole 
  AU  - Finnerty,John 
  AU  - Carroll,Sean B. 
  T1  - Conflicting Phylogenetic Signals at the Base of the Metazoan Tree.
  PY  - 2003
  UR  - http://dx.doi.org/10.1046/j.1525-142X.2003.03042.x
  N2  - A phylogenetic framework is essential for understanding the origin and evolution of metazoan development. Despite a number of recent molecular studies and a rich fossil record of sponges and cnidarians, the evolutionary relationships of the early branching metazoan groups to each other and to a putative outgroup, the choanoflagellates, remain uncertain. This situation may be the result of the limited amount of phylogenetic information found in single genes and the small number of relevant taxa surveyed. To alleviate the effect of these analytical factors in the phylogenetic reconstruction of early-branching metazoan lineages, we have cloned multiple protein-coding genes from two choanoflagellates and diverse sponges, cnidarians, and a ctenophore. Comparisons of sequences for a-tubulin, b-tubulin, Elongation Factor 2, HSP90, and HSP70 robustly support the hypothesis that choanoflagellates are closely affiliated with animals. However, analyses of single and concatenated amino acid sequences fail to resolve the relationships either between early branching metazoan groups or between Metazoa and choanoflagellates. We demonstrate that variable rates of evolution among lineages, sensitivity of the analyses to taxon selection and conflicts in the phylogenetic signal contained in different amino acid sequences obscure the phylogenetic associations among the early branching Metazoa. These factors raise concerns about the ability to resolve the phylogenetic history of animals with molecular sequences. A consensus view of animal evolution may require investigations of genome-scale characters.
  L3  - 10.1046/j.1525-142X.2003.03042.x
  JF  - Evolution & Development
  VL  - 5
  IS  - 4
  SP  - 346
  EP  - 359
  ER  -